How should sensory function in the oropharynx be tested? Cold thermal testing: a comparison of the methods of levels and limits

O Sunnergren, A Broström, E Svanborg
Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology 2010, 121 (11): 1886-9

OBJECTIVE: Several studies indicate an upper airway peripheral neuropathy in obstructive sleep apnea syndrome (OSAS). The sensation of cold, as measured by cold detection thresholds (CDT), in the oropharynx has been shown to be compromised in patients with sleep apnea and, to a lesser extent, habitual snoring. To reveal whether this neuropathy is part of the pathogenetic process of OSAS, longitudinal studies of snorers are needed. The objective of the present study was to establish the test-retest repeatability for the two most commonly used thermal testing methods: the reaction time exclusive method of levels (MLE) and the method of limits (MLI).

METHODS: Forty non-snoring subjects were tested at the soft palate and the lip at two separate occasions (mean interval 45days) using a Medoc TSA - 2001 equipment with an intra-oral thermode.

RESULTS: With MLE mean CDT's were lower for both the lip and soft palate than with MLI. However, MLI showed a better test-retest repeatability (r=2.2 vs. 2.6) for the soft palate.

CONCLUSIONS: MLI should be used in longitudinal studies. The performance of this method is also faster.

SIGNIFICANCE: We have established a quick, safe and reliable method suitable for longitudinal studies of peripheral neuropathy in sleep apnea pathogenesis.

Full Text Links

Find Full Text Links for this Article


You are not logged in. Sign Up or Log In to join the discussion.

Related Papers

Remove bar
Read by QxMD icon Read

Save your favorite articles in one place with a free QxMD account.


Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"