OPEN IN READ APP
JOURNAL ARTICLE
RANDOMIZED CONTROLLED TRIAL

Triamcinolone-impregnated nasal dressing following endoscopic sinus surgery: a randomized, double-blind, placebo-controlled study

David W J Côté, Erin D Wright
Laryngoscope 2010, 120 (6): 1269-73
20513050

OBJECTIVES/HYPOTHESIS: To evaluate the impact of steroid-impregnated absorbable nasal dressing on wound healing and surgical outcomes after endoscopic sinus surgery (ESS).

STUDY DESIGN: A prospective, randomized, double-blinded, placebo-controlled trial.

METHODS: Chronic rhinosinusitis patients with polyposis who were to undergo bilateral endoscopic sinus surgery were recruited and randomized to receive triamcinolone-impregnated bioresorbable dressing (Nasopore; Stryker Canada, Hamilton, Ontario, Canada) in one nasal cavity and saline-impregnated dressing contralaterally. Postoperative healing assessments of edema, crusting, secretions, and scarring were done at postoperative days 7, 14, 28 and at 3 and 6 months using validated Lund-Kennedy and Perioperative Sinus Endoscopy (POSE) scores.

RESULTS: Analysis of 19 enrolled patients having completed observation shows no significant difference between the cavity scores preoperatively using both the POSE and Lund-Kennedy scores. There was, however, a statistically significant difference at day 7 and 14 in both the Lund-Kennedy (P = .04 and P = .03, respectively) and POSE scores (P = .03 and P = .001, respectively) for the treatment and control groups, and a significant difference was also detected between the groups at 3- and 6-month observations (Lund-Kennedy, P = .007 and P = .02, respectively; POSE, P = .049 and P = .01, respectively).

CONCLUSIONS: Data analysis suggests a significant improvement in early postoperative healing in nasal cavities receiving triamcinolone-impregnated absorbable nasal packing following ESS and is also associated with improved healing up to 6 months postoperatively.

Discussion

You are not logged in. Sign Up or Log In to join the discussion.

Related Papers

Available on the App Store

Available on the Play Store
Remove bar
Read by QxMD icon Read
20513050
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"