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Dengue virus surveillance for early warning, Singapore.

Kim Sung Lee, Yee Ling Lai, Sharon Lo, Timothy Barkham, Pauline Aw, Peng Lim Ooi, Ji Choong Tai, Martin Hibberd, Patrik Johansson, Seow Poh Khoo, Lee Ching Ng
Emerging Infectious Diseases 2010 May
In Singapore, after a major outbreak of dengue in 2005, another outbreak occurred in 2007. Laboratory-based surveillance detected a switch from dengue virus serotype 1 (DENV-1) to DENV-2. Phylogenetic analysis showed a clade replacement within DENV-2 cosmopolitan genotype, which accompanied the predominant serotype switch, and cocirculation of multiple genotypes of DENV-3.

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