[The role of D-dimer in aortic dissection]

S Sofia, E Baldini, H Zhuzhuni, C A Velardi, E Maffongelli, A Ovani, A Coppola, M Suppa, M G Scarpellini
La Clinica Terapeutica 2010, 161 (1): 45-8

OBJECTIVES: The aim of this retrospective study is to indicate the correlation between the grade of the extent of the aortic pathology, the presence of complications, the evolution of the pathology value of the D-dimer in all the patients with aortic dissection in order to know a prognostic role a short-long time of this test.

MATERIALS AND METHODS: Only in 40 patients were possible to determine the value of D-dimer priol of these patients were not received invasive cares. The patients are divided into 4 classes in accordance with the extent of the aortic pathology valued TAC images and after we have taken in observation the presence of clinical complications shown and the positive history for chronic aortic dissection.

RESULTS: The elevation of D-dimer is strictly associated with the extent of the aortic dissection. The value of D-dimer is more elevated during the progress of the pathology and in the presence of clinical complications than during chronic aortic dissection.

CONCLUSIONS: The D-dimer is considered a diagnostic marker by the clinicians during the acute setting of the aortic dissection. A lot of points of view should be valued and cleared, its possible to attribute a prognostic role at the D-dimer during the acute aortic dissection.


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