We have located links that may give you full text access.
JOURNAL ARTICLE
RANDOMIZED CONTROLLED TRIAL
Effects of premedication of midazolam or clonidine on perioperative anxiety and pain in children.
Bioscience Trends 2009 June
The aim of the present study was to compare clinical effects of oral midazolam and clonidine premedication in children. In a prospective randomized double blind trial, 45 children between 2-8 years old received either oral midazolam 0.5 mg/kg (group M) or clonidine at 2 microg/kg (group C 2) or 4 microg/kg (group C4). The level of sedation, quality of parental separation, mask acceptance and thermodynamics were recorded. Postoperative analgesia, and perioperative side effects were assessed. In comparison to group M, the scores of sedation, parental separation and mask acceptance were significantly higher in group C2 and group C4 (p < 0.05). Also the level of sedation was significantly better in group C 4 than in group C 2 (p < 0.05). However, the rate of postoperative analgesia decreased significantly in group C 2 and C 4 compared to group M. The incidence of shivering was significantly increased in group M compared to group C 2 and C 4 . Oral clonidine premedication can therefore provide better preoperative sedation and postoperative analgesia with few adverse effects.
Full text links
Related Resources
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app
All material on this website is protected by copyright, Copyright © 1994-2024 by WebMD LLC.
This website also contains material copyrighted by 3rd parties.
By using this service, you agree to our terms of use and privacy policy.
Your Privacy Choices
You can now claim free CME credits for this literature searchClaim now
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app