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TLR2 looks at lipoproteins

Mirjam Schenk, John T Belisle, Robert L Modlin

Immunity 2009 December 18, 31 (6): 847-9

Toll-like receptors (TLRs) have evolved to recognize lipoproteins from diverse species of bacteria. In this issue of Immunity, Kang et al. (2009) provide insight into the mechanisms by which TLR2-TLR6 heterodimers recognize diacylated liporoteins, whereas TLR2-TLR1 heterodimers recognize triacylated lipopeptides.

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