We have located links that may give you full text access.
Predictors of one-year disability and death in Chinese hospitalized women after ischemic stroke.
Cerebrovascular Diseases 2010 Februrary
BACKGROUND AND PURPOSE: Women have a worse functional outcome after stroke, but the specific factors associated with a poor outcome in women are rarely reported. This study was designed to investigate the clinical predictors of 1-year disability and death in women after ischemic stroke.
METHODS: Patients with ischemic stroke consecutively registered from March 2002 to July 2007 were followed prospectively for 1 year. Multivariate regression models were employed to analyze predictors of disability (defined as modified Rankin scale score, mRS, 3-5) and death.
RESULTS: A total of 2,774 ischemic stroke patients were included with 1,119 (40.3%) females (mean age 65 +/- 13.5 years). Among female patients, disability (mRS 3-5) is 1.68-fold higher and case fatality is 1.23-fold higher than in men at the 1-year follow-up. Diabetes is an independent predictor of 1-year disability among women (odds ratio, 1.56; 95% confidence interval, CI, 1.01-2.39). In-hospital acute renal failure (hazard ratio, HR, 7.26; 95% CI, 3.47-5.19), suboptimal antiplatelets (HR, 0.55; 95% CI, 0.37-0.83) and antihypertensive therapy (HR, 0.61; 95% CI, 0.42-0.90) are associated with death at 1 year after stroke among women.
CONCLUSIONS: The present study indicates that diabetes, in-hospital acute renal failure, suboptimal antiplatelets and antihypertensive therapy are the possible explanations for the poor 1-year outcome of women hospitalized with ischemic stroke.
METHODS: Patients with ischemic stroke consecutively registered from March 2002 to July 2007 were followed prospectively for 1 year. Multivariate regression models were employed to analyze predictors of disability (defined as modified Rankin scale score, mRS, 3-5) and death.
RESULTS: A total of 2,774 ischemic stroke patients were included with 1,119 (40.3%) females (mean age 65 +/- 13.5 years). Among female patients, disability (mRS 3-5) is 1.68-fold higher and case fatality is 1.23-fold higher than in men at the 1-year follow-up. Diabetes is an independent predictor of 1-year disability among women (odds ratio, 1.56; 95% confidence interval, CI, 1.01-2.39). In-hospital acute renal failure (hazard ratio, HR, 7.26; 95% CI, 3.47-5.19), suboptimal antiplatelets (HR, 0.55; 95% CI, 0.37-0.83) and antihypertensive therapy (HR, 0.61; 95% CI, 0.42-0.90) are associated with death at 1 year after stroke among women.
CONCLUSIONS: The present study indicates that diabetes, in-hospital acute renal failure, suboptimal antiplatelets and antihypertensive therapy are the possible explanations for the poor 1-year outcome of women hospitalized with ischemic stroke.
Full text links
Related Resources
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app
All material on this website is protected by copyright, Copyright © 1994-2024 by WebMD LLC.
This website also contains material copyrighted by 3rd parties.
By using this service, you agree to our terms of use and privacy policy.
Your Privacy Choices
You can now claim free CME credits for this literature searchClaim now
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app