Hypocupremia: an under recognized cause of subacute combined degeneration

Irene Y L Tan, Lyne Noël de Tilly, Trevor A Gray
Canadian Journal of Neurological Sciences. le Journal Canadien des Sciences Neurologiques 2009, 36 (6): 779-82
It is increasingly evident that a multitude of etiologies can give rise to signal abnormality in the dorsal and lateral columns of the spinal cord, apart from pernicious anemia. We report a case of dorsal and lateral columns signal abnormality related to hypocupremia resulting in progressive sensory ataxia and weakness in the lower and upper limbs, compounded by a recent diagnosis of Sjögren's syndrome.

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