JOURNAL ARTICLE

The role of magnetic resonance imaging for acute ischemic stroke

Daniel Sanak, David Horak, Roman Herzig, Petr Hlustik, Petr Kanovsky
Biomedical Papers of the Medical Faculty of the University Palacký, Olomouc, Czechoslovakia 2009, 153 (3): 181-7
19851429

BACKGROUND: Although computed tomography (CT) is still considered to be the gold standard of brain imaging before thrombolysis, new reperfusion strategies in acute ischemic stroke lead to more extensive use of magnetic resonance imaging (MRI).

METHODS AND RESULTS: Diffusion- (DWI) and perfusion-weighted (PWI) MRI with MRI angiography are considered the most important examinations in diagnosis of acute ischemic stroke before reperfusion therapy. The effort to extend strict therapeutic time window resulted in the PWI/DWI mismatch concept, established to identify the presence of ischemic penumbra. Nevertheless, a lack of standards for methodology and analysis and existence of different alternative interpretations of such mismatch still present significant limitations of its use in routine clinical practice.

CONCLUSION: MRI allows accurate diagnosis of the infarct lesion, detection of cerebral arterial occlusion or significant stenosis with evaluation of actual collateral flow and may also display certain reversible ischemic changes. However, the main objective for MRI still remains: improvement of non-invasive rapid and accurate identification of brain tissue at risk for infarction, which may be salvaged by safe and effective reperfusion therapy.

Full Text Links

Find Full Text Links for this Article

Discussion

You are not logged in. Sign Up or Log In to join the discussion.

Related Papers

Remove bar
Read by QxMD icon Read
19851429
×

Save your favorite articles in one place with a free QxMD account.

×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"