Outcome domains for studies of acute and chronic gout

H Ralph Schumacher, William Taylor, Lawrence Edwards, Rebecca Grainger, Naomi Schlesinger, Nicola Dalbeth, Francisca Sivera, Jasvinder Singh, Robert Evans, Royce W Waltrip, Cesar Diaz-Torne, Patricia MacDonald, Fiona McQueen, Fernando Perez-Ruiz
Journal of Rheumatology 2009, 36 (10): 2342-5
Discussion and voting at OMERACT 9 confirmed 5 essential domains for outcomes of acute gout: pain, joint swelling, joint tenderness, patient global assessment and activity limitations. For studies in chronic gout 7 essential domains are: serum urate, acute gout attacks, tophus burden, health-related quality of life, activity limitations, pain, and patient global assessment. Implications of patient perspectives, discretionary domains for specific studies, measurement instruments and a possible responder index are under study.

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