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[Gastroesophageal reflux disease: pathogenetic basis of differentiated tactics of treatment].

The article contains information about severe side effects of long-term acid suppression with non-select proton pump inhibitors (PPI) treatment of gastroesophageal reflux disease (GERD). As far as concern patients with heartborn without esophagitis (non-erosive GERD) using PPI doesn't correspond the pathogenesis and hardly has any advantages. Therapy with gastric acidity inhibitors increases risk of acute gastroenteritis and community-acquired pneumonia. Quality of life is rising and symptoms of gastro-esophageal reflux are getting away thanks to topical harmless treatment GERD without severe esophagitis Pepsan-R.

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