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Astemizole-induced cardiac conduction disturbances in a child.

J R Tobin, T P Doyle, A D Ackerman, J I Brenner
JAMA 1991 November 21
The newly available antihistamine astemizole (Hismanal) has been previously associated with hemodynamically significant cardiac tachydysrhythmias. We describe a 3-year-old girl who developed multiple different cardiac dysrhythmias after an astemizole overdose. No hemodynamic compromise occurred, and the electrocardiogram returned to normal without use of antiarrhythmic agents within 7 hours.

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