Argon laser peripheral iridoplasty for topiramate-induced bilateral acute angle closure.

PURPOSE: To report a case of a topiramate-induced bilateral acute angle closure that was treated successfully by argon laser peripheral iridoplasty (ALPI).

METHODS: A 59-year-old healthy woman taking oral topiramate developed bilateral acute angle closure. B-scan ultrasonography, ultrasound biomicroscopy, and slit-lamp adapted ocular coherence tomography were performed.

RESULTS: The patient had shallow anterior chambers and total angle closure for 360 degrees OU. Ocular imaging showed circumferential ciliochoroidal effusions with anterior displacement of the iris-lens diaphragm. ALPI relieved the angle closure.

CONCLUSIONS: ALPI should be considered as initial therapy for topiramate-induced acute angle closure.