The effects of resorbable membrane on human maxillary sinus graft: a pilot study

Kyung-Soo Choi, Joseph Y K Kan, Philip J Boyne, Charles J Goodacre, Jaime L Lozada, Kitichai Rungcharassaeng
International Journal of Oral & Maxillofacial Implants 2009, 24 (1): 73-80

PURPOSE: To investigate the effects of resorbable membrane on new bone formation in human maxillary sinus graft using anorganic bovine bone material histomorphometrically in a split-mouth study design.

MATERIALS AND METHODS: This prospective pilot study included six patients who required bilateral sinus augmentations prior to implant treatment. Each patient was grafted with anorganic bovine bone (Bio-Oss). The experimental side was covered with resorbable membrane (Bio-Gide) over the grafted sinus, and the control side was left uncovered. After 8 months of healing (range, 7 to 9 months), implants were placed. Biopsy samples were obtained from each side through the previously grafted sinus window and evaluated. Statistical analysis was performed using the Mann-Whitney U test at a significance level of alpha = .05.

RESULTS: The control side appeared to have a significantly greater amount of soft tissue than the experimental side (P = .026), whereas no significant differences in the amount of new bone were observed (P = .937).

CONCLUSION: Resorbable membranes significantly reduced the amount of soft tissue formed in the sinus grafted with anorganic bovine bone material but had no effect on new bone formation.

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