COMPARATIVE STUDY
JOURNAL ARTICLE

Evidence of diversification of dengue virus type 3 genotype III in the South American region

Domenica de Mora, Lucía D' Andrea, Macarena Alvarez, Mary Regato, Alvaro Fajardo, Ricardo Recarey, Rodney Colina, Baldip Khan, Juan Cristina
Archives of Virology 2009, 154 (4): 699-707
19322636
In order to gain insight into the genetic variability of dengue virus type 3 (DENV-3) genotype III isolated in the Latin American region, phylogenetic analysis were carried out using envelope (E) gene sequences from 57 DENV-3 genotype III strains isolated in 11 Latin American countries. At least six different genotype III clades were observed. Amino acids substitutions were found in domain III E protein neutralization epitopes and in surface-exposed domain II and III E protein amino acid sequences.

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