JOURNAL ARTICLE
REVIEW

Acanthosis nigricans: a practical approach to evaluation and management

Steven P Higgins, Michael Freemark, Neil S Prose
Dermatology Online Journal 2008, 14 (9): 2
19061584
Acanthosis nigricans is a dermatosis characterized by thickened, hyperpigmented plaques, typically of the intertriginous surfaces and neck. Common in some populations, its prevalence depends on race. Clinicians should recognize acanthosis nigricans; it heralds disorders ranging from endocrinologic disturbances to malignancy. In this review, we discuss the pathogenesis of acanthosis nigricans and its clinical implications and management.

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