DNA-embedded Au/Ag core-shell nanoparticles

Dong-Kwon Lim, In-Jung Kim, Jwa-Min Nam
Chemical Communications: Chem Comm 2008 November 14, (42): 5312-4
Here, we synthesized highly stable DNA-embedded Au/Ag core-shell nanoparticles (NPs) by a straightforward silver-staining of DNA-modified Au nanoparticles (AuNPs); unlike conventional DNA-surface modified NPs that present particle stability issues, DNA-embedded core-shell NPs offer an extraordinary stability with nanoscale controllability of silver shell thickness; these DNA-embedded core-shell NPs show excellent biorecognition properties and Ag shell-thickness-based optical properties, distinctively different from those of a mixture of AuNPs and AgNPs or Ag/Au alloy nanoparticles.

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