Coexistence of struma ovarii with marked ascites and elevated CA-125 levels: case report and literature review

Mabel Po Mui, Kar-Fai Tam, Fiona K Y Tam, Hextan Y S Ngan
Archives of Gynecology and Obstetrics 2009, 279 (5): 753-7

INTRODUCTION: Struma ovarii is a rare form of ovarian neoplasm and consists mainly of thyroid tissue. Ascites has been reported in approximately one-third of all the cases. However, the combination of struma ovarii and elevated CA-125 has rarely been reported.

MATERIALS AND METHODS: We described a case of benign struma ovarii, presenting with the clinical features of ovarian cancer: large complex pelvic mass, gross ascites and markedly elevated serum CA-125 levels. Surgical excision of the ovarian mass was followed by rapid resolution of the ascites and reduction of the serum CA-125 level.

CONCLUSION: Struma ovarii can mimic ovarian malignancy clinically, when presented with ascites and an elevated CA-125 level.

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