JOURNAL ARTICLE

[Safety and feasibility of laparoscopic surgery and open surgery in ulcerative colitis: a meta-analysis]

Xiao-jian Wu, Xiao-sheng He, Xu-yu Zhou, Yi-feng Zou, Ping Lan
Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery 2008, 11 (5): 408-13
18803038

OBJECTIVE: To compare the safety and feasibility of laparoscopic surgery and open surgery in ulcerative colitis.

METHODS: A search of published studies in English and Chinese between January 1992 and May 2008 was performed. Nine hundred and twenty-three patients from 16 studies were recruited which met the inclusion criteria. Meta-analysis was performed through fixed effect model or random effect model dependent on heterogeneity.

RESULTS: Compared to open procedure, patients with ulcerative colitis undergone laparoscopic surgery were able to tolerate oral intake significantly earlier (P<0.01) with shorter hospital stay (P<0.01) and had lower total complication rate (P<0.01). But duration of laparoscopic surgery was significantly longer than that of open procedure(P=0.04). Laparoscopic procedure was no more superior to open procedure in recovery of bowel function, re-operation rate, intra-abdominal abscess, anastomotic leak, postoperative bowel obstruction, wound infection, blood loss and mortality. The conversion rate was 4.2% in this analysis.

CONCLUSION: Laparoscopic surgery for ulcerative colitis is safe and feasible with better recovery in short-term as compared to the open procedure.

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