Evidence for the co-circulation of dengue virus type 3 genotypes III and V in the Northern region of Brazil during the 2002-2004 epidemics
Meri Bordignon Nogueira, Vanessa Stella, Juliano Bordignon, Weber Cheli Batista, Luana de Borba, Luis Hildebrando Pereira da Silva, Federico Guillermo Hoffmann, Christian Macagnan Probst, Claudia Nunes Duarte dos Santos
Memórias do Instituto Oswaldo Cruz 2008, 103 (5): 483-8
18797763
The reintroduction of dengue virus type 3 (DENV-3) in Brazil in 2000 and its subsequent spread throughout the country was associated with genotype III viruses, the only DENV-3 genotype isolated in Brazil prior to 2002. We report here the co-circulation of two different DENV-3 genotypes in patients living in the Northern region of Brazil during the 2002-2004 epidemics. Complete genomic sequences of viral RNA were determined from these epidemics, and viruses belonging to genotypes V (Southeast Asia/South Pacific) and III were identified. This recent co-circulation of different DENV-3 genotypes in South America may have implications for pathological and epidemiological dynamics.
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