JOURNAL ARTICLE

Case control MR-CISS and 3D TOF MRA imaging study of medullary compression and hypertension in hemifacial spasm

Ling-Ling Chan, Esther Lee, Stephanie Fook-Chong, Eng-King Tan
Movement Disorders: Official Journal of the Movement Disorder Society 2008 October 15, 23 (13): 1820-4
18709669
The association between ventro-lateral medulla (VLM) compression and hypertension has not been compared between hemifacial spasm (HFS) and healthy controls using advanced magnetic resonance imaging (MRI) techniques specific for detecting neurovascular compression. We conducted a MR-constructive interference in a steady state (CISS) and Magnetic Resonance Angiography (MRA) imaging study of VLM compression in hypertensive HFS patients and hypertensive controls compared with healthy controls without hypertension. A total of 125 subjects, including 45 HFS, 51 healthy controls, and 29 hypertensive controls were included. When compared with healthy controls, there was a higher prevalence of VLM compression in hypertensive HFS (82.2% vs. 41.2%, P < 0.001, odds ratio = 6.61, 95% CI 2.37-19.48), and hypertensive controls (72.4% vs. 41.2%, P = 0.007, odds ratio = 3.75, 95% CI 1.42-9.89). Although the prevalence in hypertensive HFS was higher compared to controls with hypertension, this was not significant (82.2% vs. 72.4%). Compared to healthy controls, there was an increasing proportion of higher compression scores on the right (P = 0.001) and left (P = 0.038) (chi square for trend) in hypertensive HFS and hypertensive controls. Kruskal-Wallis test revealed that the mean right compression score on the right (P = 0.003), left (P = 0.026) and the mean bilateral compression score (P < 0.0001) was higher in hypertensive HFS and hypertensive controls compared to healthy controls. MR-CISS and MRA imaging revealed a greater likelihood of VLM compression in hypertensive HFS and hypertensive controls compared to healthy controls. Our case control study provides further support that VLM compression is associated with hypertension in HFS.

Full Text Links

Find Full Text Links for this Article

Discussion

You are not logged in. Sign Up or Log In to join the discussion.

Related Papers

Remove bar
Read by QxMD icon Read
18709669
×

Save your favorite articles in one place with a free QxMD account.

×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"