COMPARATIVE STUDY
JOURNAL ARTICLE

EUS-guided fine needle aspiration with and without trucut biopsy of pancreatic masses

Syed Mubashir Shah, Afonso Ribeiro, Joe Levi, Merce Jorda, Caio Rocha-Lima, Danny Sleeman, Kara Hamilton-Nelson, Parvin Ganjei-Azar, Jamie Barkin
JOP: Journal of the Pancreas 2008, 9 (4): 422-30
18648133

CONTEXT: Endoscopic ultrasound-guided trucut biopsy (EUS TCB) has a lower yield than fine needle aspiration (FNA) in pancreatic masses but the additional use of TCB to FNA may improve the diagnostic accuracy over FNA alone.

OBJECTIVE: To compare the yield of EUS FNA alone or combined with EUS TCB for diagnosis of pancreatic masses.

DESIGN: Single center retrospective case control study conducted at academic tertiary center. Study conducted between March 2004 and April 2007.

PARTICIPANTS: A total of 126 consecutive patients referred for EUS guided biopsy of pancreatic mass; three patients excluded from analysis, final cohort comprised 123 patients (108 malignant and 15 benign). EUS FNA was performed in 72 patients and EUS FNA+TCB was performed in 51 patients.

MAIN OUTCOME MEASURES: The diagnostic performance of EUS FNA versus EUS FNA+TCB was compared.

RESULTS: The sensitivity, specificity and frequency of cases correctly identified for malignancy of FNA alone were 87.1% (54/62), 100% (10/10) and 88.8% (64/72), while for the combination of FNA+TCB they were: 95.7% (44/46), 100% (5/5) and 96.0% (49/51), respectively (P=0.184, 1.000, and 0.193 FNA versus FNA+TCB). No major complication occurred in either group.

CONCLUSION: FNA+TCB can be safely performed in selected lesions but sensitivity is not statistically improved over FNA alone (95.7% versus 87.1%).

Full Text Links

Find Full Text Links for this Article

Discussion

You are not logged in. Sign Up or Log In to join the discussion.

Related Papers

Remove bar
Read by QxMD icon Read
18648133
×

Save your favorite articles in one place with a free QxMD account.

×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"