Acanthosis nigricans associated with primary hypogonadism: successful treatment with topical calcipotriol

Stamatis Gregoriou, Vasilis Anyfandakis, Panagiotis Kontoleon, Eleftheria Christofidou, Dimitris Rigopoulos, George Kontochristopoulos
Journal of Dermatological Treatment 2008, 19 (6): 373-5
Acanthosis nigricans is a mucocutaneous dermatosis characterized by hyperpigmentation and a velvety papillomatous hyperkeratosis. It is frequently associated with systemic diseases including malignancy and endocrinal disorders. We report the beneficial effect of topical calcipotriol ointment 50 mcg/g twice a day in acanthosis nigricans associated with primary hypogonadism.

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