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Pediatric hypothyroidism presenting with a polymyositis-like syndrome and increased creatinine: report of three cases.

Anne Marie Sbrocchi, Gaëlle Chédeville, Rosie Scuccimarri, Ciarán M Duffy, Preetha Krishnamoorthy
Journal of Pediatric Endocrinology & Metabolism : JPEM 2008 January
We report three pediatric cases of primary hypothyroidism presenting with musculoskeletal complaints, elevated muscle enzymes and increased creatinine. Thyroid hormone replacement led to improvement in both the clinical features and laboratory abnormalities.

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