JOURNAL ARTICLE
REVIEW
Add like
Add dislike
Add to saved papers

The post-anaphylaxis dilemma: how long is long enough to observe a patient after resolution of symptoms?

Anaphylaxis may recur 1 to 72 hours after initial signs and symptoms apparently resolve. Reported incidence of biphasic anaphylaxis varies from 1% to 23%. Late-phase severity varies from mild to severe (rarely fatal). No evidence or expert consensus presently identifies distinguishing characteristics in the initial phase that predict a late phase. However, reports propose potential risk factors, including initial phase severity, delayed or suboptimal doses of epinephrine during initial treatment, laryngeal edema or hypotension during initial phase, delayed symptomatic onset after antigen exposure, or history of biphasic anaphylaxis. It is unclear whether systemic corticosteroids administered in the initial phase can prevent or weaken late-phase reactions. Based on available evidence, observation periods after complete resolution of uniphasic anaphylaxis should be individualized, particularly because there are no reliable predictors of biphasic anaphylaxis. A 10-hour observation period appears sufficient, but some investigators recommend 24 hours.

Full text links

For the best experience, use the Read mobile app

Group 7SearchHeart failure treatmentPapersTopicsCollectionsEffects of Sodium-Glucose Cotransporter 2 Inhibitors for the Treatment of Patients With Heart Failure Importance: Only 1 class of glucose-lowering agents-sodium-glucose cotransporter 2 (SGLT2) inhibitors-has been reported to decrease the risk of cardiovascular events primarily by reducingSeptember 1, 2017: JAMA CardiologyAssociations of albuminuria in patients with chronic heart failure: findings in the ALiskiren Observation of heart Failure Treatment study.CONCLUSIONS: Increased UACR is common in patients with heart failure, including non-diabetics. Urinary albumin creatininineJul, 2011: European Journal of Heart FailureRandomized Controlled TrialEffects of Liraglutide on Clinical Stability Among Patients With Advanced Heart Failure and Reduced Ejection Fraction: A Randomized Clinical Trial.Review

Get seemless 1-tap access through your institution/university

For the best experience, use the Read mobile app

Read by QxMD is copyright © 2021 QxMD Software Inc. All rights reserved. By using this service, you agree to our terms of use and privacy policy.

You can now claim free CME credits for this literature searchClaim now

Get seemless 1-tap access through your institution/university

For the best experience, use the Read mobile app