JOURNAL ARTICLE

Arterial and venous response to Tilt with LBNP test after a 60 day HDT bedrest (WISE study)

P Arbeille, P Kerbeci, D Greaves, S Schneider, A Hargens, R Hughson
Journal of Gravitational Physiology: a Journal of the International Society for Gravitational Physiology 2007, 14 (1): P47-8
18372693

UNLABELLED: The objective was to quantify the Cerebral, and Femoral arterial hemodynamics as well as the calf vein section changes induced by a Tilt up test continuing with a Tilt plus LBNP after a 60 day HDT (WISE).

METHOD: 24 healthy volunteers (25-40 y) underwent a 60 day HDT (-6 degree) bedrest: 8 as Control (Co), 8 with Exercise (Ex: treadmill under LBNP and flywheel), 8 with Nutrition (Nut: daily protein supplement). At R+0 all of them underwent a 10 min 80 degree Tilt up test, to which several LBNP period of 3 min were added (from -10 to -50 mmHg by steps of 10 mmHg) until presyncopal stage. Cerebral and Femoral flow changes were assessed by Doppler. Posterior Tibial, and Gastrocnemian vein were investigated by echography.

RESULTS: At Post HDT 10 min Tilt: cerebral flow decreased similarly in the 3 groups, but more in the non finishers than in the finishers, while the femoral decreased similarly in all groups. Leg vascular resistance and cerebral/femoral flow ratio increased less in the Co and Nut gr than in the Ex gr, and also in the non finishers than in the finishers. Percent increase in Gastrocnemian and Tibial section was higher in Co and Nut gr than in Ex gr, and in non finishers than in finishers.

CONCLUSION: Non exercise and non finisher subjects showed a lack of leg vasoconstriction, and a higher calf vein distensibility at post HDT Tilt test.

Full Text Links

Find Full Text Links for this Article

Discussion

You are not logged in. Sign Up or Log In to join the discussion.

Related Papers

Remove bar
Read by QxMD icon Read
18372693
×

Save your favorite articles in one place with a free QxMD account.

×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"