New insights into the control of stem cell pluripotency

Paul J Gokhale, Peter W Andrews
Cell Stem Cell 2008 January 10, 2 (1): 4-5
Nanog is a transcription factor that is expressed by mouse and human embryonic stem (ES) cells and by primordial germ cells. New research published recently in Nature (Chambers et al., 2007) points to an unexpected role for Nanog in the maintenance of pluripotency in mouse ES cells.

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