Intragastric alendronate therapy in two infants with vitamin D intoxication: a new method

Hakan Doneray, Behzat Ozkan, Ibrahim Caner, Asuman Ozkan, Cahit Karakelleoglu
Clinical Toxicology 2008, 46 (4): 300-2
In recent years, alendronate, an oral biphosphonate, has been added to therapy of hypercalcemia secondary to vitamin D intoxication in children. Alendronate may cause mucosal ulcerations in the mouth and esophagus. We report our experience in two infants with vitamin D intoxication to whom alendronate therapy was administered through nasogastric tube, an alternate route for alendronate administration.

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