Follow-up after surgery for benign nodular thyroid disease: evidence-based approach

Roy Phitayakorn, Christopher R McHenry
World Journal of Surgery 2008, 32 (7): 1374-84

BACKGROUND: There is no consensus on what constitutes appropriate methodology and timing for follow-up of patients after surgery for benign nodular disease.

METHODS: A systematic review of the medical literature using evidence-based criteria was used to address the following four issues: (1) How often should patients who have undergone thyroidectomy for the treatment of benign nodular goiter be followed, and what constitutes appropriate follow-up? (2) What is the most appropriate method for detecting recurrent nodular thyroid disease? (3) Does thyroid hormone administration prevent recurrent nodular thyroid disease? (4) Does iodine administration prevent recurrent nodular thyroid disease?

RESULTS: Altogether, 742 articles were found in MEDLINE using a keyword search strategy; we then narrowed them to 23 articles. There were a total of four articles with Level I data, five articles with Level II data, one article with Level III data, and 13 articles with Level IV or retrospective data.

CONCLUSIONS: Based on the available data, it is our recommendation that patients undergoing thyroid lobectomy for benign nodular thyroid disease should be followed with an annual physical examination, neck ultrasonography, and serum thyroid-stimulating hormone (TSH) measurement. Patients undergoing total thyroidectomy should be followed with an annual physical examination and a serum TSH measurement. Routine thyroxine and/or iodine supplementation may be useful for preventing recurrence in patients from iodine-deficient regions.

Full Text Links

Find Full Text Links for this Article


You are not logged in. Sign Up or Log In to join the discussion.

Related Papers

Remove bar
Read by QxMD icon Read

Save your favorite articles in one place with a free QxMD account.


Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"

We want to hear from doctors like you!

Take a second to answer a survey question.