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Orbital invasion despite topical anti-metabolite therapy for conjunctival carcinoma.

Devron H Char, J Brooks Crawford
Graefe's Archive for Clinical and Experimental Ophthalmology 2008 March
BACKGROUND: Two cases of conjunctival carcinoma developed orbital invasion during treatment with topical medication.

METHODS: This was a retrospective study from a tertiary ophthalmic oncology unit, performed after informed consent was obtained. The main outcome measurement was orbital invasion.

RESULTS: Two patients treated with topical agents developed orbital invasion.

CONCLUSION: While topical agents are important in treatment of conjunctival neoplasia, recurrence or deep invasion require careful monitoring.

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