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JOURNAL ARTICLE
RANDOMIZED CONTROLLED TRIAL
Validating an Ataxia Functional Composite Scale in spinocerebellar ataxia.
Journal of the Neurological Sciences 2008 May 16
The Ataxia Functional Composite Scale (AFCS) may provide a sensitive and reproducible assessment of treatment responses in studies of the spinocerebellar ataxias (SCA). We previously assessed the effects of buspirone in a cohort of patients with SCA via the International Cooperative Ataxia Rating Scale (ICARS). At each assessment period, AFCS scores were also obtained. A strong correlation of AFCS with ICARS scores was demonstrated at all assessment periods. This study supports the validity of the AFCS as a useful assessment of ataxia in this population.
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