[The ameloblastic fibro-odontoma—an odontogenic mixed tumor progressing into an odontogenic sarcoma]

U Herzog, H P Putzke, V Bienengräber, C Radke
Deutsche Zeitschrift Für Mund-, Kiefer- und Gesichts-Chirurgie 1991, 15 (2): 90-3
A case report is given on the rare course of an ameloblastic odontoma which originated from the right mandible in a girl at the age of 14. During the follow-up of 12 years there where 4 recurrences with a change in the histological findings. While ameloblastic epithelial complexes were found to be ever decreasing, there was, on the other hand, an increase in the mesenchymal component with foci of a marked proliferation of spindle cellular fibroblastic elements. Finally the condition progressed to an ameloblastic odontosarcoma appearing as a pleomorphic fibrosarcoma with a local metastasis. The clinical behaviour correlated with the histopathological findings.

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