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Bicycle riding, perineal trauma, and erectile dysfunction: data and solutions.

Significant clinical and basic science advances in the field of sexual medicine have facilitated investigation of the link between endothelial dysfunction and erectile dysfunction. Most sexual medicine practitioners accept the premise that in aging men with risk factors such as increased waist circumference, diabetes, hypertension, hypogonadism, hypercholesterolemia, and insulin insensitivity, a higher prevalence of erectile dysfunction reflects systemic vasculopathy that often first presents as abnormal erectile function. Endothelial dysfunction in the pudendal, common penile, and cavernosal arterial bed can occur secondary to pelvic, perineal, or penile trauma in young men without traditional systemic vascular risk factors. Because some younger men with erectile dysfunction may have underlying vasculogenic erectile dysfunction, sexual medicine practitioners should perform sophisticated testing procedures to evaluate erectile function that can be reestablished with penile revascularization surgery.

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Group 7SearchHeart failure treatmentPapersTopicsCollectionsEffects of Sodium-Glucose Cotransporter 2 Inhibitors for the Treatment of Patients With Heart Failure Importance: Only 1 class of glucose-lowering agents-sodium-glucose cotransporter 2 (SGLT2) inhibitors-has been reported to decrease the risk of cardiovascular events primarily by reducingSeptember 1, 2017: JAMA CardiologyAssociations of albuminuria in patients with chronic heart failure: findings in the ALiskiren Observation of heart Failure Treatment study.CONCLUSIONS: Increased UACR is common in patients with heart failure, including non-diabetics. Urinary albumin creatininineJul, 2011: European Journal of Heart FailureRandomized Controlled TrialEffects of Liraglutide on Clinical Stability Among Patients With Advanced Heart Failure and Reduced Ejection Fraction: A Randomized Clinical Trial.Review

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