JOURNAL ARTICLE

Whole-body and thoracic bioimpedance measurement: hypertension and hyperhydration in hemodialysis patients

L Nescolarde, P Bogónez, J Calpe, R Hernández, T Doñate, J Rosell
Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society 2007, 2007: 3593-6
18002774
Mono-frequency (50 kHz) and multi-frequency (3 kHz - 1 MHz) whole-body and thoracic segment bioimpedance measurement were doing before and after hemodialysis session in 20 patients. The patients were classified in hypertensive or non-hypertensive according to the mean blood pressure, BPmean. The relation between hyper-hydration in thorax segment through real part of impedance and mean blood pressure was analyzed. Also the bioelectrical impedance vector analysis method was used to analyze the displacement of Z/H vector in order to establish the relation with hyper-hydration (edema). Finally we made multi-frequency measurements with the objective to find a significative change in high and low frequency. We obtained a significant difference (P < 0.05) in impedance parameters before and after HD session. Some patients are located in hyper-hydration zone, below the inferior pole of the 75% tolerance ellipse, whereas others patients were within the tolerance ellipses. The real part of the impedance in thorax region can identify over-hydrated patients with an increased risk for cardiovascular disease associate to hypertension. Multi-frequency bioimpedance measurement show an important change at low and high frequency and indicate that is possible to obtain more information about extra-cellular or intra-cellular fluid status, to find the relation between fluid loads, bioimpedance parameters, extra-cellular water, and blood pressure.

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