We have located links that may give you full text access.
JOURNAL ARTICLE
RESEARCH SUPPORT, N.I.H., EXTRAMURAL
REVIEW
Posterior circulation stroke and animal models.
The posterior circulation is part of the brain circulation that is subject to stroke. Strokes which involve the posterior circulation account for approximately 25% of all ischemic strokes, and about 10-20% of all hemorrhagic strokes. While the mortality rate from ischemic strokes in posterior circulation could be as low as 4%, the cerebellar and pontine hemorrhages carry a mortality rate close to 20% and 60%, respectively mainly due to brainstem compression secondary to edema or from direct parenchymal damage to vital cardio-respiratory centers. There are very few therapies geared towards neuroprotection or for reduction of edema in the posterior circulation. In fact, most treatments for anterior circulation stroke are commonly used for the posterior circulation, without an adequate study of the benefits and drawbacks. Since multiple neurovascular differences exist between these two circulations, this would imply that additional studies are needed to refine the clinical treatments in the posterior region. This review summarizes the existing animal models for posterior circulation stroke or vascular insufficiency, and discusses the anatomical, histological, neuronal, neurobehavioral and neurovascular differences at the hindbrain in comparison to the forebrain.
Full text links
Related Resources
Trending Papers
Heart failure with preserved ejection fraction: diagnosis, risk assessment, and treatment.Clinical Research in Cardiology : Official Journal of the German Cardiac Society 2024 April 12
Proximal versus distal diuretics in congestive heart failure.Nephrology, Dialysis, Transplantation 2024 Februrary 30
World Health Organization and International Consensus Classification of eosinophilic disorders: 2024 update on diagnosis, risk stratification, and management.American Journal of Hematology 2024 March 30
Efficacy and safety of pharmacotherapy in chronic insomnia: A review of clinical guidelines and case reports.Mental Health Clinician 2023 October
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app
All material on this website is protected by copyright, Copyright © 1994-2024 by WebMD LLC.
This website also contains material copyrighted by 3rd parties.
By using this service, you agree to our terms of use and privacy policy.
Your Privacy Choices
You can now claim free CME credits for this literature searchClaim now
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app