Extensive iliac vein thrombosis as a rare complication of a uterine leiomyoma: a case report.

BACKGROUND: Lower leg thombosis can occur in association with a large uterine leiomyoma.

CASE: We report a case of extensive lower extremity thromboembolic disease secondary to large uterine myomas. The patient presented with sudden onset of lower extremity swelling in the absence of risk factors for thrombosis. Workup revealed extensive thrombosis involving iliac, femoral, popliteal, posterior tibial and peroneal veins secondary to vena caval compression by large uterine fibroids. Hysterectomy was performed after vena caval filter placement.

CONCLUSION: In women with large uterine leiomyomas, the preoperative workup should include testing to rule out potential asymptomatic thrombi.