In vitro hypoglycemic activity of methanolic extract of some indigenous plants

M Saeed Arayne, Najma Sultana, Agha Zeeshan Mirza, M Hashim Zuberi, Farhan Ahmed Siddiqui
Pakistan Journal of Pharmaceutical Sciences 2007, 20 (4): 268-73
Pakistan is rich in medicinally important plants and has ancient herbal treatment methods. Present work is based on the study of six indigenous plants Eugenia jambolana, Lawsonia inermis, Momordica charantia, Morus alba, Nigella sativa and Trigonella foenum graecum which show the inhibitory effect of glucose utilization, and are in use as hypoglycemic agents of varying degree in traditional system of medicine. The glucose uptake activity of (methanolic extracts) of these plants was tested in vitro and glucose was estimated by glucose oxidase method. The results in three different media revealed that, hypoglycemic activity is more prominent in neutral and basic media as compared to acidic medium.

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