We have located links that may give you full text access.
Journal Article
Review
[Cerebral venous thrombosis--diagnosis and treatment].
BACKGROUND: Cerebral venous thrombosis (CVT) is a rare cause of stroke, and an important differential diagnosis for a number of neurological complaints. This review article concerns the aetiology, pathology, diagnostic work-up and treatment of the condition.
MATERIAL AND METHODS: This article is based on a review of relevant literature and on the authors' personal experience.
RESULTS AND INTERPRETATION: CVT is thought to be responsible for about 0.5-1.0% of all strokes. Headache is the initial symptom in 70-90% of the cases. Apart from this, symptoms vary considerably. CVT was previously assumed to be a rare condition with a high mortality, as the diagnosis could in effect only be made post mortem. Conditions with a benign course can now be diagnosed with modern neuroradiological examinations. All patients should be assessed carefully; particular attention should be given to possible congenital or acquired forms of thrombophilia. Scepsis about the use of anticoagulants in CVT has long prevailed, especially in connection with haemorrhagic infarcts. During the last 10-15 years, several studies indicate that anticoagulation with heparin, or low-molecular heparin, should be the initial treatment of choice. Catheter-based endovascular thrombolytic treatment should be considered in serious cases where anticoagulant treatment is unsuccessful. Mortality is about 10%.
MATERIAL AND METHODS: This article is based on a review of relevant literature and on the authors' personal experience.
RESULTS AND INTERPRETATION: CVT is thought to be responsible for about 0.5-1.0% of all strokes. Headache is the initial symptom in 70-90% of the cases. Apart from this, symptoms vary considerably. CVT was previously assumed to be a rare condition with a high mortality, as the diagnosis could in effect only be made post mortem. Conditions with a benign course can now be diagnosed with modern neuroradiological examinations. All patients should be assessed carefully; particular attention should be given to possible congenital or acquired forms of thrombophilia. Scepsis about the use of anticoagulants in CVT has long prevailed, especially in connection with haemorrhagic infarcts. During the last 10-15 years, several studies indicate that anticoagulation with heparin, or low-molecular heparin, should be the initial treatment of choice. Catheter-based endovascular thrombolytic treatment should be considered in serious cases where anticoagulant treatment is unsuccessful. Mortality is about 10%.
Full text links
Related Resources
Trending Papers
Challenges in Septic Shock: From New Hemodynamics to Blood Purification Therapies.Journal of Personalized Medicine 2024 Februrary 4
Molecular Targets of Novel Therapeutics for Diabetic Kidney Disease: A New Era of Nephroprotection.International Journal of Molecular Sciences 2024 April 4
The 'Ten Commandments' for the 2023 European Society of Cardiology guidelines for the management of endocarditis.European Heart Journal 2024 April 18
A Guide to the Use of Vasopressors and Inotropes for Patients in Shock.Journal of Intensive Care Medicine 2024 April 14
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app
All material on this website is protected by copyright, Copyright © 1994-2024 by WebMD LLC.
This website also contains material copyrighted by 3rd parties.
By using this service, you agree to our terms of use and privacy policy.
Your Privacy Choices
You can now claim free CME credits for this literature searchClaim now
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app