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CLINICAL TRIAL
JOURNAL ARTICLE
Efficacy of pulsed dye laser in facial port-wine stains in Indian patients.
Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.] 2007 May
BACKGROUND: Facial port-wine stain (PWS) produces severe cosmetic disfigurement and pulsed dye laser (PDL) has revolutionized the treatment of PWS.
OBJECTIVE: To assess the efficacy of PDL for facial PWS in Indian patients.
MATERIALS AND METHODS: Twenty-seven patients of Fitzpatrick skin types IV and V in the age group of 8 to 34 years (mean 21.6 years), with lesional size 3 x 1.5 to 25 x 19 cm and color from light pink to deep red and violaceous, were recruited. Laser parameters were spot size, 7 mm; fluence, 5 to 7.5 J/cm(2); wavelength, 585 nm, pulse duration, 0.45 ms; along with continuous air cooling. Response at every session was graded from 0 to 5+(0, no improvement; 1+, up to 25%; 2+, 26% to 50%; 3+, 51% to 75%; 4 +, 76% to 99%; 5+, 100% lightening).
RESULTS: In a total of 170 sessions, maximum response of 1+ was observed in 6 patients after mean of 3.5 sessions, 2+ in 8 patients after mean of 5.25 sessions, 3+ in 8 patients after mean of 7 sessions, and 4+ improvement in 5 patients after mean of 4.8 sessions. No patient showed complete clearance. Seven patients developed hyperpigmentation while 1 patient showed hypopigmentation, but none had textural change or scarring.
CONCLUSION: PDL offers significant cosmetic improvement in facial PWS in Indian patients.
OBJECTIVE: To assess the efficacy of PDL for facial PWS in Indian patients.
MATERIALS AND METHODS: Twenty-seven patients of Fitzpatrick skin types IV and V in the age group of 8 to 34 years (mean 21.6 years), with lesional size 3 x 1.5 to 25 x 19 cm and color from light pink to deep red and violaceous, were recruited. Laser parameters were spot size, 7 mm; fluence, 5 to 7.5 J/cm(2); wavelength, 585 nm, pulse duration, 0.45 ms; along with continuous air cooling. Response at every session was graded from 0 to 5+(0, no improvement; 1+, up to 25%; 2+, 26% to 50%; 3+, 51% to 75%; 4 +, 76% to 99%; 5+, 100% lightening).
RESULTS: In a total of 170 sessions, maximum response of 1+ was observed in 6 patients after mean of 3.5 sessions, 2+ in 8 patients after mean of 5.25 sessions, 3+ in 8 patients after mean of 7 sessions, and 4+ improvement in 5 patients after mean of 4.8 sessions. No patient showed complete clearance. Seven patients developed hyperpigmentation while 1 patient showed hypopigmentation, but none had textural change or scarring.
CONCLUSION: PDL offers significant cosmetic improvement in facial PWS in Indian patients.
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