JOURNAL ARTICLE

Negative filament tension in the Luo-Rudy model of cardiac tissue

S Alonso, A V Panfilov
Chaos 2007, 17 (1): 015102
17411259
Scroll waves are vortices that occur in three-dimensional excitable media. Scroll waves have been observed in a variety of systems including cardiac tissue, where they are associated with cardiac arrhythmias. The disorganization of scroll waves into chaotic behavior is thought to be the mechanism of ventricular fibrillation, which lethality is widely known. One of the possible mechanisms of scroll wave instability is negative filament tension, which was studied theoretically using low-dimensional models of excitable medium. In this article we perform a numerical study of negative filament tension using the Luo-Rudy phase 1 model, which is widely used in cardiac electrophysiology. We show that this instability exists in this model, study its manifestation and discuss its relation to cardiac arrhythmogenesis.

Full Text Links

Find Full Text Links for this Article

Discussion

You are not logged in. Sign Up or Log In to join the discussion.

Related Papers

Remove bar
Read by QxMD icon Read
17411259
×

Save your favorite articles in one place with a free QxMD account.

×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"