JOURNAL ARTICLE
RANDOMIZED CONTROLLED TRIAL

Effect of low tidal volume ventilation on atelectasis in patients during general anesthesia: a computed tomographic scan

Hongwei Cai, Hua Gong, Lina Zhang, Yanjin Wang, Yuke Tian
Journal of Clinical Anesthesia 2007, 19 (2): 125-9
17379125

STUDY OBJECTIVE: To determine whether low tidal ventilation in patients without lung injury results in an increase in the amount of atelectasis and a further impairment of gas exchange during general anesthesia.

DESIGN: Randomized, single-blind study.

SETTING: University hospital.

PATIENTS: 16 adult, ASA physical status I and II patients, who were scheduled for elective excision of intracranial lesion.

INTERVENTIONS: Patients were randomly allocated to one of two groups: traditional tidal volume (V(T)) ventilation group (V(T), 10 mL/kg) and low V(T) ventilation group (V(T), 6 mL/kg) after the first computed tomographic (CT) scan.

MEASUREMENTS AND MAIN RESULTS: Atelectasis, as determined by CT and arterial blood gas analysis, was measured before induction, after tracheal intubation, and at the end of operation. After tracheal intubation, CT scan showed atelectasis in both groups. The mean atelectasis area was 4.25 +/- 2.05 cm(2) (3.32% +/- 1.94%) in the traditional V(T) ventilation group and 5.56 +/- 3.21 cm(2) (4.19% +/- 2.31%) in the low V(T) ventilation group. At the end of operation, there was no significant increase in the amount of atelectasis within the two groups. Arterial blood gas analysis showed no differences after tracheal intubation or at the end of operation in either group.

CONCLUSION: Ventilation using low V(T)s does not cause more pulmonary collapse than mechanical ventilation using standard V(T)s.

Full Text Links

Find Full Text Links for this Article

Discussion

You are not logged in. Sign Up or Log In to join the discussion.

Related Papers

Remove bar
Read by QxMD icon Read
17379125
×

Save your favorite articles in one place with a free QxMD account.

×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"