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Contribution of procalcitonin to occult bacteraemia detection in children.

Christele Gras-Le Guen, Caroline Delmas, Elise Launay, Jocelyne Caillon, Virginie Loubersac, Georges Picherot, J Christophe Roze
Scandinavian Journal of Infectious Diseases 2007
We conducted a prospective study in 215 children, 3 to 36 months of age, presenting with fever > or = 39 degrees C without obvious origin, in order to evaluate the diagnostic value of procalcitonin (PCT) in detection of occult bacteraemia. PCT associated with white blood cell count constitutes an efficient screening method with sensitivity 100%, specificity 61.9% and positive and negative likelihoods ratios of 2.62 and 0, respectively.

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