JOURNAL ARTICLE

Myasthenia gravis and pregnancy

M Kalidindi, S Ganpot, F Tahmesebi, A Govind, S Okolo, W Yoong
Journal of Obstetrics and Gynaecology: the Journal of the Institute of Obstetrics and Gynaecology 2007, 27 (1): 30-2
17365454
Myasthenia gravis (MG) is a chronic autoimmune disorder of neuromuscular transmission characterized by varying degrees of weakness and easy fatigability of the skeletal muscles. Precipitants of myasthenic symptoms or crises include physical and emotional stress, systemic illness, infections, hypo or hyperthyroidism, pregnancy, any type of surgery with general anaesthesia as well as corticosteroids. The authors report two cases of MG in pregnancy and discuss briefly the various aspects of the disease course and management in pregnancy. As MG occurs predominantly in women of reproductive years, it is important that obstetricians are aware of this condition and its management in pregnancy.

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