Primary Sjö-gren's syndrome presenting with distal, renal tubular acidosis and rhabdomyolysis

E B S Prakash, M E Fernando, Malathi Sathiyasekaran, R M Bhoopathy, J J Jayanth, J Samuel
Journal of the Association of Physicians of India 2006, 54: 949-50
Primary Sjögren's syndrome (PSS) is rare in India. Clinically manifest renal disease in PSS is uncommon and is usually an autoimmune tubulointerstitial nephritis presenting with distal renal tubular acidosis (dRTA) or a urinary concentrating defect. Hypokalemic paralysis due to dRTA in PSS is rare but well documented in medical literature. Rhabdomyolysis as a consequence of hypokalemia in PSS is exceptional. We report a case of PSS with dRTA and rhabdomyolysis causing prolonged respiratory failure and quadriparesis.

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