A case of haemodialysis-associated pseudoporphyria successfully treated with oral N-acetylcysteine

N S Cooke, K McKenna
Clinical and Experimental Dermatology 2007, 32 (1): 64-6
We report a 33-year-old woman with haemodialysis-associated pseudoporphyria successfully responding to treatment with oral N-acetylcysteine. We briefly review the current literature on bullous skin disorders in end-stage renal disease, and compare and contrast the pathogenesis of pseudoporphyria and porphyria cutanea tarda in this context. We also discuss the antioxidant properties and clinical applications of N-acetylcysteine, including the treatment of haemodialysis-associated pseudoporphyria.

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