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CASE REPORTS
JOURNAL ARTICLE
Epithelioid osteosarcoma presenting as a rapidly expanding maxillary mass.
Head & Neck 2007 July
BACKGROUND: Osteosarcomas of the jaws account for less than 10% of reported neoplasms of this type. Patients with osteosarcoma in this region tend to be in the late-third to mid-fourth decades of life. The osteoblastic, chondroblastic, and fibroblastic variants constitute the majority of lesions.
METHODS: A mass was observed in the maxilla of a 50-year-old male who presented for a complete odontectomy. Over the ensuing weeks, the mass substantially increased in size, despite multimodality treatment efforts.
RESULTS: Radiographic findings revealed a mixed density mass of the left maxilla. Histologic, immunohistochemical, and electron microscopy examination of the tumor showed a malignant mesenchymal neoplasm consisting of sheets of epithelioid and spindle cells exhibiting focal osteoid formation.
CONCLUSIONS: We report a rare and aggressive case of epithelioid osteosarcoma arising in the maxillofacial complex.
METHODS: A mass was observed in the maxilla of a 50-year-old male who presented for a complete odontectomy. Over the ensuing weeks, the mass substantially increased in size, despite multimodality treatment efforts.
RESULTS: Radiographic findings revealed a mixed density mass of the left maxilla. Histologic, immunohistochemical, and electron microscopy examination of the tumor showed a malignant mesenchymal neoplasm consisting of sheets of epithelioid and spindle cells exhibiting focal osteoid formation.
CONCLUSIONS: We report a rare and aggressive case of epithelioid osteosarcoma arising in the maxillofacial complex.
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