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Coronary artery anatomy in children with congenital heart disease by computed tomography

Shyh-Jye Chen, Ming-Tai Lin, Wen-Jeng Lee, Kao-Lang Liu, Jou-Kou Wang, Chung-I Chang, Yiu-Wah Li, Ing-She Chiu
International Journal of Cardiology 2007 September 3, 120 (3): 363-70

AIMS: To evaluate electron beam computed tomography (EBCT) for recognition of coronary artery patterns in children with congenital heart diseases.

METHODS: Institutional review board approval was obtained; informed consents were not required. A total of 226 children diagnosed with Tetralogy of Fallot (n=122), double outlet right ventricle (n=52), transposition of the great arteries (n=34), and congenitally corrected transposition (n=18) who had undergone cardiac EBCT at our institution between 1995 and 2002 were identified. Iodinated contrast medium was injected with arterial phase acquisition. The two radiologists and one pediatric cardiologist that interpreted the EBCT images and cardiac angiograms, respectively, were blinded to each other's results. Surgical and cardiac angiogram findings were compared to the EBCT results. Descriptive statistics were used to compare efficacy.

RESULTS: Numerous aberrant patterns were clearly identified on the EBCT images. Pattern IX occurred in most patients with Tetralogy of Fallot or double outlet right ventricle. Patterns I and 0 are the most common coronary artery types in transposition of the great arteries and congenitally corrected transposition, respectively. Overall diagnostic accuracy for all disease groups was 82.7%. The diagnostic accuracy of the coronary arterial anatomy by EBCT increased with older age, and was more than 90% in individuals aged over 3 months.

CONCLUSION: EBCT is effective for identification of the coronary anatomy of children with specific congenital heart diseases, except for neonates and small infants less than 3 months of age.

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