Respiratory variations in pulse oximeter waveform amplitude are influenced by venous return in mechanically ventilated patients under general anaesthesia

M Cannesson, O Desebbe, M Hachemi, D Jacques, O Bastien, J-J Lehot
European Journal of Anaesthesiology 2007, 24 (3): 245-51

BACKGROUND AND OBJECTIVES: Respiratory variations in pulse oximetry plethysmographic waveform amplitude (DeltaPOP) are related to respiratory variations in arterial pulse pressure (DeltaPP) in the critical care setting. The aims of this study were to test the hypothesis that in mechanically ventilated patients undergoing general anaesthesia, DeltaPOP calculation is feasible and can detect changes in preload.

METHODS: Twenty-five mechanically ventilated patients were studied immediately after induction of general anaesthesia. Haemodynamic data (mean arterial pressure [MAP], central venous pressure [CVP], DeltaPP and DeltaPOP) were recorded at baseline, before and after tilting the patient from anti-Trendelenburg to Trendelenburg position in order to induce preload changes.

RESULTS: Change from anti-Trendelenburg to Trendelenburg position induced changes in MAP (58 +/- 9 to 67 +/- 10 mmHg, P < 0.05), CVP (4 +/- 4 to 13 +/- 5 mmHg, P < 0.05), DeltaPP (14 +/- 8 to 7 +/- 5%, P < 0.05) and DeltaPOP (17 +/- 12 to 9 +/- 5%, P < 0.05). There was a significant relationship between DeltaPOP in anti-Trendelenburg position and percent change in MAP after volume expansion (r = 0.82; P < 0.05).

CONCLUSIONS: DeltaPOP can be determined in the operating room and is influenced by changes in preload. This new index has potential clinical applications for the prediction of fluid responsiveness.

Full Text Links

Find Full Text Links for this Article


You are not logged in. Sign Up or Log In to join the discussion.

Related Papers

Remove bar
Read by QxMD icon Read

Save your favorite articles in one place with a free QxMD account.


Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"