Presence of the exoU gene of Pseudomonas aeruginosa is correlated with cytotoxicity in MDCK cells but not with colonization in BALB/c mice

Hsi-Hsun Lin, Shiao-ping Huang, Hsiu-Chen Teng, Dar-Der Ji, Yao-Shen Chen, Ya-Lei Chen
Journal of Clinical Microbiology 2006, 44 (12): 4596-7
A total of 141 independent strains of Pseudomonas aeruginosa with different heterogeneities in the exo gene (exoS, exoT, exoU, and exoY) background were examined for their pathogenic roles. Results indicated that the exoU gene is the major contributor to cytotoxicity in Madin-Darby canine kidney cells but is not related to bacterial colonization in mice.


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