The relationship between migraine and right-to-left shunt: Fact or fiction?

Martijn C Post, Werner Budts
Chest 2006, 130 (3): 896-901
The prevalence of a right-to-left shunt, both cardiac and pulmonary, is high in patients with migraines, especially migraine with aura. Percutaneous closure of a right-to-left shunt seems to be associated with a pronounced decrease in the number of migraine attacks or its prevalence. In this review, the relationship between migraine and right-to-left shunting is described by highlighting the different pathophysiologic hypotheses.

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